Open AccessPartially Melted Ti6Al4V Particles Increase Bacterial Adhesion and Inhibit Osteogenic Activity on 3D-printed Implants: An In Vitro Study
Author(s) -
Keliang Xie,
Guoqing Yu,
Shuang Zhao,
Lei Wang,
Jinlong Wu,
Jia Tan,
Yangzi Yang,
Wen Wu,
Wenbo Jiang,
Yongqiang Hao
Publication year - 2019
Publication title -
clinical orthopaedics and related research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.178
H-Index - 204
eISSN - 1528-1132
pISSN - 0009-921X
DOI - 10.1097/corr.0000000000000954
Subject(s) - osseointegration , adhesion , biofilm , materials science , titanium , biomedical engineering , implant , titanium alloy , medicine , composite material , surgery , bacteria , alloy , metallurgy , biology , genetics
A porous Ti6Al4V implant that is manufactured using selective laser melting (SLM) has broad potential applications in the field of orthopaedic implants. The pore structure of the SLM porous Ti6Al4V implant allows for cell migration and osteogenic differentiation, which is favorable for bone ingrowth and osseointegration. However, it is unclear whether the pore structure and partially melted Ti6Al4V particles on a SLM porous Ti6Al4V implant will increase bacterial adhesion and, perhaps, the risk of implant-related infection.