Open AccessIs Implant Coating With Tyrosol- and Antibiotic-loaded Hydrogel Effective in Reducing Cutibacterium (Propionibacterium) acnes Biofilm Formation? A Preliminary In Vitro Study
Author(s) -
Konstantinos Tsikopoulos,
Alessandro Bidossi,
Lorenzo Drago,
D. R. Petrenyov,
Panagiotis Givissis,
Dimitris Mavridis,
Paraskevi Papaioannidou
Publication year - 2019
Publication title -
clinical orthopaedics and related research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.178
H-Index - 204
eISSN - 1528-1132
pISSN - 0009-921X
DOI - 10.1097/corr.0000000000000663
Subject(s) - propionibacterium acnes , tyrosol , biofilm , microbiology and biotechnology , minimum bactericidal concentration , minimum inhibitory concentration , medicine , rifampicin , antibiotics , bacteria , chemistry , biology , food science , acne , olive oil , dermatology , genetics
Studies have suggested that Cutibacterium acnes (formerly known as Propionibacterium) is the most frequently isolated pathogen after shoulder arthroplasty. To address the burden of periprosthetic joint infections associated with this pathogen, new prevention methods are needed. Tyrosol has a promising record of effectiveness in the field of biofilm-associated infections; however, to our knowledge, it has not been tested against C. acnes thus far.