Open AccessChemotherapy Curtails Bone Formation From Compliant Compression Fixation of Distal Femoral Endoprostheses
Author(s) -
Mohammad A. Elalfy,
Patrick J. Boland,
John H. Healey
Publication year - 2018
Publication title -
clinical orthopaedics and related research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.178
H-Index - 204
eISSN - 1528-1132
pISSN - 0009-921X
DOI - 10.1097/corr.0000000000000512
Subject(s) - medicine , fixation (population genetics) , surgery , environmental health , population
Modulated compliant compressive forces may contribute to durable fixation of implant stems in patients with cancer who undergo endoprosthetic reconstruction after tumor resection. Chemotherapy effects on bone hypertrophy and osteointegration have rarely been studied, and no accepted radiologic method exists to evaluate compression-associated hypertrophy.