Open AccessPsychologic Factors Do Not Affect Placebo Responses After Upper Extremity Injections: A Randomized Trial
Author(s) -
Tom J. Crijns,
Teun Teunis,
Neal C. Chen,
David Ring
Publication year - 2018
Publication title -
clinical orthopaedics and related research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.178
H-Index - 204
eISSN - 1528-1132
pISSN - 0009-921X
DOI - 10.1097/corr.0000000000000425
Subject(s) - medicine , placebo , lidocaine , physical therapy , visual analogue scale , dash , randomized controlled trial , anxiety , minimal clinically important difference , anesthesia , nocebo , surgery , psychiatry , alternative medicine , pathology , computer science , operating system
Studies on how psychologic factors influence the placebo effect have shown conflicting results in an experimental setting. Pessimists are more likely to experience a nocebo effect (feel worse after an inert intervention), whereas other studies suggest that patients with more symptoms of depression or anxiety or greater neuroticism have a greater response to a placebo. This is important because treatment benefits are potentiated by placebo effects, and optimal utilization of this phenomenon may improve clinical outcomes.