Open AccessTechnologies for HIV-1 drug resistance testing: inventory and needs
Author(s) -
Karin J. Metzner
Publication year - 2022
Publication title -
current opinion in hiv and aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.901
H-Index - 64
eISSN - 1746-6318
pISSN - 1746-630X
DOI - 10.1097/coh.0000000000000737
Subject(s) - sanger sequencing , dna sequencing , genotyping , human immunodeficiency virus (hiv) , drug resistance , computational biology , hiv drug resistance , medicine , biology , viral load , genetics , virology , antiretroviral therapy , gene , genotype
HIV-1 drug resistance (HIV DR) testing is routinely performed by genotyping plasma viruses using Sanger population sequencing. Next-generation sequencing (NGS) is increasingly replacing standardized Sanger sequencing. This opens up new opportunities, but also brings challenges.