Open AccessVisualization of HIV-1 reservoir: an imaging perspective
Author(s) -
Catherine Chapon,
Eirini Moysi,
Thibaut Naninck,
Céline Mayet,
Constantinos Petrovas
Publication year - 2021
Publication title -
current opinion in hiv and aids
Language(s) - English
Resource type - Journals
eISSN - 1746-6318
pISSN - 1746-630X
DOI - 10.1097/coh.0000000000000691
Subject(s) - human immunodeficiency virus (hiv) , computational biology , antiretroviral therapy , simian immunodeficiency virus , disease , biology , computer science , medicine , virology , viral load , pathology
The persistence of HIV-1-infected cells, despite the introduction of the combinatorial antiretroviral therapy, is a major obstacle to HIV-1 eradication. Understanding the nature of HIV reservoir will lead to novel therapeutic approaches for the functional cure or eradication of the virus. In this review, we will update the recent development in imaging applications toward HIV-1/simian immunodeficiency virus (SIV) viral reservoirs research and highlight some of their limitations.