Open AccessPrognostic Value of the Tumor Immune Microenvironment for Early-stage, Non−Small Cell Lung Cancer
Author(s) -
Stephanie Tuminello,
Francesca Petralia,
Rajwanth Veluswamy,
Pei Wang,
Raja M. Flores,
Emanuela Taioli
Publication year - 2021
Publication title -
american journal of clinical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.896
H-Index - 78
eISSN - 1537-453X
pISSN - 0277-3732
DOI - 10.1097/coc.0000000000000832
Subject(s) - medicine , lung cancer , hazard ratio , adenocarcinoma , proportional hazards model , immune system , oncology , cd8 , stage (stratigraphy) , tumor microenvironment , cytotoxic t cell , immunotherapy , confidence interval , cancer , immunology , biology , paleontology , biochemistry , in vitro
The role of specific immune cell types within the tumor immune microenvironment in non-small cell lung cancer survival is unclear. The potential of these immune cells to become predictive biomarkers of prognosis, and to define subpopulations who will benefit of additional treatment is urgently needed.