Open AccessBreast-conservation Therapy After Neoadjuvant Chemotherapy Does Not Compromise 10-Year Breast Cancer–specific Mortality
Author(s) -
Renee L. Arlow,
Lisa E. Paddock,
Xiaoling Niu,
Laurie Kirstein,
Bruce G. Haffty,
Sharad Goyal,
Thomas Kearney,
Deborah Toppmeyer,
Antoinette Stroup,
Atif J. Khan
Publication year - 2018
Publication title -
american journal of clinical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.896
H-Index - 78
eISSN - 1537-453X
pISSN - 0277-3732
DOI - 10.1097/coc.0000000000000456
Subject(s) - medicine , breast cancer , mastectomy , lumpectomy , hazard ratio , radiation therapy , oncology , breast conserving surgery , neoadjuvant therapy , chemotherapy , proportional hazards model , cancer , confidence interval , surgery
Neoadjuvant chemotherapy can increase the rate of breast-conserving surgery by downstaging disease in patients with breast cancer. The aim of this study was to determine whether patients who received neoadjuvant chemotherapy have equal survival after breast-conservation therapy compared with mastectomy.