Open AccessSystematic analysis on expression quantitative trait loci identifies a novel regulatory variant in ring finger and WD repeat domain 3 associated with prognosis of pancreatic cancer
Author(s) -
Ying Zhu,
Xiaobo Peng,
Xiaoyang Wang,
Pingting Ying,
Haoxue Wang,
Bin Li,
Yue Li,
Ming Zhang,
Yimin Cai,
Zequn Lu,
Siyuan Niu,
Nan Yang,
Rong Zhong,
Jianbo Tian,
Jiang Chang
Publication year - 2022
Publication title -
chinese medical journal/chinese medical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 63
eISSN - 2542-5641
pISSN - 0366-6999
DOI - 10.1097/cm9.0000000000002180
Subject(s) - biology , gene , phenotype , genetics , pancreatic cancer , computational biology , cancer
Pancreatic adenocarcinoma (PAAD) is an extremely lethal malignancy. Identification of the functional genes and genetic variants related to PAAD prognosis is important and challenging. Previously identified prognostic genes from several expression profile analyses were inconsistent. The regulatory genetic variants that affect PAAD prognosis were largely unknown.