Open AccessCircular RNAs in peripheral blood mononuclear cells from ankylosing spondylitis
Author(s) -
Yiping Tang,
QuanBo Zhang,
Fei Dai,
Xia Liao,
Zeng-Rong Dong,
Tao Yi,
Yufeng Qing
Publication year - 2021
Publication title -
chinese medical journal/chinese medical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 63
eISSN - 2542-5641
pISSN - 0366-6999
DOI - 10.1097/cm9.0000000000001815
Subject(s) - circular rna , microrna , peripheral blood mononuclear cell , fold change , microbiology and biotechnology , rna , microarray , biology , ankylosing spondylitis , non coding rna , messenger rna , real time polymerase chain reaction , transcriptome , downregulation and upregulation , immunology , gene expression , gene , genetics , in vitro
Circular RNA (circRNA) is a type of closed circular noncoding RNA (ncRNA), mostly formed by back-splicing or alternative splicing of pre-messenger RNA (mRNA). The aim of this study was to explore the expression profile of circRNA in peripheral blood mononuclear cells (PBMCs) of patients with ankylosing spondylitis (AS) and discover potential molecular markers of AS.