Open AccessAssessment of causal association between thyroid function and lipid metabolism: a Mendelian randomization study
Author(s) -
Jingjia Wang,
Zhenhuang Zhuang,
Chunli Shao,
Canqing Yu,
Wenyao Wang,
Kuo Zhang,
Xiaoxue Meng,
Jun Gao,
Jianwei Tian,
Jilin Zheng,
Tao Huang,
YiDa Tang
Publication year - 2021
Publication title -
chinese medical journal/chinese medical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 63
eISSN - 2542-5641
pISSN - 0366-6999
DOI - 10.1097/cm9.0000000000001505
Subject(s) - mendelian randomization , medicine , endocrinology , thyroid function , lipid metabolism , thyroid , thyroid peroxidase , triiodothyronine , lipoprotein , cholesterol , biology , genetics , genotype , genetic variants , gene
Thyroid dysfunction is associated with cardiovascular diseases. However, the role of thyroid function in lipid metabolism remains partly unknown. The present study aimed to investigate the causal association between thyroid function and serum lipid metabolism via a genetic analysis termed Mendelian randomization (MR).