Open AccessGenome-wide DNA methylation patterns in monocytes derived from patients with primary Sjogren syndrome
Author(s) -
Xuan Luo,
Yu Peng,
Yingying Chen,
Anqi Wang,
Chuiwen Deng,
Linyi Peng,
Qingjun Wu,
Yan Zhao,
Yunyun Fei,
Wen Zhang
Publication year - 2021
Publication title -
chinese medical journal/chinese medical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 63
eISSN - 2542-5641
pISSN - 0366-6999
DOI - 10.1097/cm9.0000000000001451
Subject(s) - dna methylation , methylation , epigenetics , biology , pathogenesis , gene , peripheral blood mononuclear cell , cell cycle , immunology , microbiology and biotechnology , gene expression , genetics , in vitro
Epigenetics, especially DNA methylation, plays an important role in the pathogenesis of primary Sjogren syndrome (pSS). Our study aimed to reveal the role of DNA methylation in peripheral monocytes of pSS patients.