Open AccessMicroRNA-23a reduces lipopolysaccharide-induced cellular apoptosis and inflammatory cytokine production through Rho-associated kinase 1/sirtuin-1/nuclear factor-kappa B crosstalk
Author(s) -
Xiaojun Shi,
Jin Ye,
Weiming Xu,
Qing Sunny Shen,
Jun Li,
Kang Chen
Publication year - 2021
Publication title -
chinese medical journal/chinese medical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 63
eISSN - 2542-5641
pISSN - 0366-6999
DOI - 10.1097/cm9.0000000000001369
Subject(s) - sepsis , apoptosis , lipopolysaccharide , cytokine , medicine , inflammation , chemistry , endocrinology , cancer research , immunology , biochemistry
MicroRNAs are closely associated with the progression and outcomes of multiple human diseases, including sepsis. In this study, we examined the role of miR-23a in septic injury.