Open AccessPreliminary adipose removal did not prevent diet-induced metabolic disorders in mice
Author(s) -
Lin Liu,
Ce Liang,
Xiaowei Wang,
Ke-Xin Pei,
Xindi Ma,
Chunxi Zhang,
Jiajia Dong,
Mingming Gao,
Jiawei Liao
Publication year - 2021
Publication title -
chinese medical journal/chinese medical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 63
eISSN - 2542-5641
pISSN - 0366-6999
DOI - 10.1097/cm9.0000000000001334
Subject(s) - adipose tissue , medicine , endocrinology , insulin resistance , cd36 , obesity , hyperlipidemia , triglyceride , diabetes mellitus , cholesterol , receptor
Obesity is a fundamental factor in metabolic disorders such as hyperlipidemia, insulin resistance, fatty liver, and atherosclerosis. However, effective preventive measures are still lacking. This study aimed to investigate different surgical protocols for removing partial adipose tissue before the onset of obesity and determine whether, and by which protocol, preliminary adipose removal could exert potent preventive effects against diet-induced metabolic disorders.