Open AccessPandemic of the aging society — sporadic cerebral small vessel disease
Author(s) -
Amy HingLing Lau,
Bonaventure Ip,
Ho Ko,
Bonnie Yin Ka Lam,
Lin Shi,
Karen Ka Yan,
Lisa Au,
Yannie Soo,
Thomas Wai Hong Leung,
Adrian Wong,
Vincent Chung Tong Mok
Publication year - 2021
Publication title -
chinese medical journal/chinese medical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 63
eISSN - 2542-5641
pISSN - 0366-6999
DOI - 10.1097/cm9.0000000000001320
Subject(s) - disease , pandemic , magnetic resonance imaging , medicine , neuroscience , population , pathology , covid-19 , psychology , environmental health , infectious disease (medical specialty) , radiology
Age-related sporadic cerebral small vessel disease (CSVD) has gained increasing attention over the past decades because of its increasing prevalence associated with an aging population. The widespread application of and advances in brain magnetic resonance imaging in recent decades have significantly increased researchers' understanding in the in vivo evolution of CSVD, its impact upon the brain, its risk factors, and the mechanisms that explain the various clinical manifestation associated with sporadic CSVD. In this review, we aimed to provide an update on the pathophysiology, risk factors, biomarkers, and the determinants and spectrum of the clinical manifestation of sporadic CSVD.