Open AccessIncreased early activation of CD56dimCD16dim/- natural killer cells in immunological non-responders correlates with CD4+ T-cell recovery
Author(s) -
Qiuyue Zhang,
Xin Zhang,
Bin Su,
Lifeng Liu,
Xiaodong Yang,
Bin Tang,
Huan Xia,
Ping Ma,
Tong Zhang,
Hao Wu
Publication year - 2020
Publication title -
chinese medical journal/chinese medical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 63
eISSN - 2542-5641
pISSN - 0366-6999
DOI - 10.1097/cm9.0000000000001262
Subject(s) - cd16 , nkg2d , flow cytometry , immunology , natural killer cell , immune system , cell , t cell , biology , medicine , cd3 , cd8 , cytotoxic t cell , in vitro , biochemistry , genetics
Natural killer (NK) cells play a critical role in suppressing human immunodeficiency virus-1 (HIV-1) infection, but knowledge on whether and how NK cells affect immune reconstitution in HIV-1-infected individuals who receive antiretroviral therapy (ART) is limited.