Open AccessSafety and efficacy of allogeneic natural killer cell immunotherapy on human immunodeficiency virus type 1 immunological non-responders: a brief report
Author(s) -
Huan Xia,
Yin Wang,
Huali Sun,
Lina Gao,
Yu Cao,
Silvere D. Zaongo,
Rong-Nan Zeng,
Hao Wu,
Mingjie Zhang,
Ping Ma
Publication year - 2020
Publication title -
chinese medical journal/chinese medical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 63
eISSN - 2542-5641
pISSN - 0366-6999
DOI - 10.1097/cm9.0000000000001189
Subject(s) - medicine , immunotherapy , immunology , cd8 , immune system , antigen , natural killer cell , randomized controlled trial , repeated measures design , cytotoxic t cell , biology , in vitro , biochemistry , statistics , mathematics
Allogeneic natural killer (NK) cell immunotherapy is recognized as a promising anti-tumor strategy, but whether it plays a role in poor CD4 recovery among human immunodeficiency virus type 1 (HIV-1) infected patients is unknown. This study aimed to investigate the safety and effectiveness of allogeneic NK cells immunotherapy on HIV-1 immunological non-responders (INRs) receiving antiretroviral therapy (ART).