Open AccessHigher serum angiopoietin 2 levels are independently associated with coronary microvascular dysfunction in patients with angina in the absence of obstructive coronary artery disease
Author(s) -
Shaomin Chen,
Dan Li,
Xing Xing,
Zhaoping Li
Publication year - 2020
Publication title -
chinese medical journal/chinese medical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 63
eISSN - 2542-5641
pISSN - 0366-6999
DOI - 10.1097/cm9.0000000000000812
Subject(s) - medicine , coronary flow reserve , cardiology , coronary artery disease , natriuretic peptide , odds ratio , angina , receiver operating characteristic , confidence interval , logistic regression , myocardial infarction , heart failure
Angiopoietin-2 (Ang-2) is a type of endothelial growth factor involved in angiogenesis and vascular remodeling. Circulating Ang-2 levels are elevated in patients with obstructive coronary artery disease (CAD). This study aimed to evaluate the association between serum Ang-2 levels and coronary microvascular dysfunction in patients without obstructive CAD.