Open AccessLong non-coding RNA small nucleolar RNA host gene 6 aggravates pancreatic cancer through upregulation of far upstream element binding protein 1 by sponging microRNA-26a-5p
Author(s) -
Xingxing Zhang,
Hua Chen,
Huiying Li,
Rui Chen,
Lei He,
Juan-Li Yang,
Linlin Xiao,
Jinlian Chen
Publication year - 2020
Publication title -
chinese medical journal/chinese medical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 63
eISSN - 2542-5641
pISSN - 0366-6999
DOI - 10.1097/cm9.0000000000000758
Subject(s) - pancreatic cancer , microrna , downregulation and upregulation , biology , rna , microbiology and biotechnology , cancer research , reporter gene , gene expression , gene , cancer , genetics
Pancreatic cancer (PC) is a highly deadly malignancy with few effective therapies. We aimed to unmask the role that long non-coding RNA small nucleolar RNA host gene 6 (SNHG6) plays in PC cells by targeting far upstream element binding protein 1 (FUBP1) via microRNA-26a-5p (miR-26a-5p).