Open AccessVascular endothelial growth factor concentration in vitreous humor of patients with severe proliferative diabetic retinopathy after intravitreal injection of conbercept as an adjunctive therapy for vitrectomy
Author(s) -
Bing Li,
Meng-Da Li,
Junjie Ye,
Zhe Chen,
Zijian Guo,
Yu Di
Publication year - 2020
Publication title -
chinese medical journal/chinese medical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 63
eISSN - 2542-5641
pISSN - 0366-6999
DOI - 10.1097/cm9.0000000000000687
Subject(s) - medicine , diabetic retinopathy , vitrectomy , proliferative vitreoretinopathy , ophthalmology , retinopathy , vascular endothelial growth factor , diabetes mellitus , retinal detachment , neovascularization , retinal , surgery , visual acuity , vegf receptors , angiogenesis , endocrinology
Proliferative diabetic retinopathy (PDR) is a progressive stage of diabetic retinopathy featured by the formation of neovascular and proliferative membrane. Vascular endothelial growth factor (VEGF) acts as a pivot factor in the development of neovascularization. This study was to investigate the changes of intravitreal VEGF concentrations of severe PDR after intravitreal injection of conbercept (IVC) and its potential advantages to the following vitrectomy.