Open AccessRelationship between serum C3/C4 ratio and prognosis of immunoglobulin A nephropathy based on propensity score matching
Author(s) -
Yan Zhang,
Shuwei Duan,
Pu Chen,
Zhimin Yin,
Yong Wang,
Guangyan Cai,
Xiangmei Chen
Publication year - 2020
Publication title -
chinese medical journal/chinese medical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 63
eISSN - 2542-5641
pISSN - 0366-6999
DOI - 10.1097/cm9.0000000000000674
Subject(s) - medicine , propensity score matching , creatinine , nephropathy , confidence interval , kidney disease , gastroenterology , retrospective cohort study , renal function , proportional hazards model , endocrinology , diabetes mellitus
Aberrant activation of the complement system plays an important role in the pathogenesis and development of immunoglobulin A nephropathy (IgAN). The relationship between serum complement and the clinical-histopathological features and outcomes of IgAN is controversial. This retrospective study aimed to examine the relationship between the complement 3/4 (C3/C4) ratio and the clinicopathologic changes and prognosis of patients with IgAN.