Open AccessPrognostic value of tumor-infiltrating lymphocyte subtypes in residual tumors of patients with triple-negative breast cancer after neoadjuvant chemotherapy
Author(s) -
Yuge Bai,
Guoxuan Gao,
Hong Zhao,
Shuang Zhang,
Yinhua Liu,
Xuening Duan,
Ling Xu
Publication year - 2020
Publication title -
chinese medical journal/chinese medical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 63
eISSN - 2542-5641
pISSN - 0366-6999
DOI - 10.1097/cm9.0000000000000656
Subject(s) - medicine , tumor infiltrating lymphocytes , breast cancer , triple negative breast cancer , oncology , chemotherapy , anthracycline , neoadjuvant therapy , cancer , immunotherapy
After neoadjuvant chemotherapy (NAC), non-pathological complete response of breast cancer patients can benefit from tailored adjuvant chemotherapy. However, it is difficult to select patients with poorer prognosis for additional adjuvant chemotherapy to maximize the benefits. Our study aimed to explore whether the subtypes of tumor-infiltrating lymphocytes (TILs) in residual tumors (RT) is related to the prognosis of triple-negative breast cancer (TNBC) after NAC.