Open AccessSphingosine-1-phosphate signal transducer and activator of transcription 3 signaling pathway contributes to baicalein-mediated inhibition of dextran sulfate sodium-induced experimental colitis in mice
Author(s) -
Jing Yao,
Tao Liu,
Ruijiao Chen,
Jing Liang,
Jun Li,
Chuangong Wang
Publication year - 2020
Publication title -
chinese medical journal/chinese medical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 63
eISSN - 2542-5641
pISSN - 0366-6999
DOI - 10.1097/cm9.0000000000000627
Subject(s) - colitis , pharmacology , sphingosine , baicalein , stat protein , sphingosine 1 phosphate , chemistry , stat3 , medicine , endocrinology , receptor , signal transduction , biochemistry
Baicalein has been shown to have anti-inflammatory and anti-tumor activities. However, the mechanisms underlying its anti-inflammatory effect on colitis remain unclear.