Open AccessLong non-coding RNA HOTAIRM1 promotes proliferation and inhibits apoptosis of glioma cells by regulating the miR-873-5p/ZEB2 axis
Author(s) -
Yihai Lin,
Liang Guo,
Feng Yan,
Zhangqi Dou,
Yu Qin,
Chen Gao
Publication year - 2019
Publication title -
chinese medical journal/chinese medical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 63
eISSN - 2542-5641
pISSN - 0366-6999
DOI - 10.1097/cm9.0000000000000615
Subject(s) - u87 , apoptosis , microrna , glioma , cancer research , cell growth , cell culture , reporter gene , glioblastoma , blot , biology , gene , gene expression , microbiology and biotechnology , genetics
Glioblastoma is one of the most common malignant brain tumors. Conventional clinical treatment of glioblastoma is not sufficient, and the molecular mechanism underlying the initiation and development of this disease remains unclear. Our study aimed to explore the expression and function of miR-873a-5p in glioblastoma and related molecular mechanism.