Open AccessAnimal models of emphysema
Author(s) -
Gongping Liang,
Zhijun He
Publication year - 2019
Publication title -
chinese medical journal/chinese medical journal
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 63
eISSN - 2542-5641
pISSN - 0366-6999
DOI - 10.1097/cm9.0000000000000469
Subject(s) - copd , medicine , animal model , pulmonary emphysema , pathological , animal species , intensive care medicine , pulmonary function testing , pulmonary disease , pathology , lung , biology , zoology
Chronic obstructive pulmonary disease (COPD) is a common chronic respiratory disease of human beings characterized by not fully reversible airflow limitation. Emphysema is the main pathological feature of COPD which causes high mortality worldwide every year and consumes a large amount of medical expenses. This paper was to review the establishment and evaluation methods of animal models of emphysema or COPD, and put forward some new ideas on animal selection, method of modeling, and model evaluation.