Open AccessOptimal strategy of switching from clopidogrel to ticagrelor in Chinese acute coronary syndrome patients with complicated coronary artery disease
Author(s) -
Ying Yao,
Ping Wang,
Xiaozeng Wang,
Xin Zhao,
Wei Zhao,
Tienan Zhou,
Lei Zhang
Publication year - 2019
Publication title -
chinese medical journal/chinese medical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 63
eISSN - 2542-5641
pISSN - 0366-6999
DOI - 10.1097/cm9.0000000000000444
Subject(s) - ticagrelor , medicine , clopidogrel , acute coronary syndrome , percutaneous coronary intervention , coronary artery disease , conventional pci , cardiology , clinical endpoint , loading dose , aspirin , myocardial infarction , randomized controlled trial
The dose and time point for switching from clopidogrel to ticagrelor remain controversial, especially for Chinese acute coronary syndrome (ACS) patients with complicated coronary artery disease (CAD). Hence, the purpose of this study was to further explore the optimal dose and time point for the switching strategy to balance the increase in platelet inhibition and the decrease in adverse events in Chinese ACS patients with complicated CAD managed by percutaneous coronary intervention (PCI).