Open AccessRole and mechanism of matrine alone and combined with acitretin for HaCaT cells and psoriasis-like murine models
Author(s) -
Weiwei Jiang,
Yimeng Wang,
Xiaoyu Wang,
Qian Zhang,
Si-Man Zhu,
Chunlei Zhang
Publication year - 2019
Publication title -
chinese medical journal/chinese medical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 63
eISSN - 2542-5641
pISSN - 0366-6999
DOI - 10.1097/cm9.0000000000000412
Subject(s) - hacat , matrine , psoriasis , acitretin , pharmacology , apoptosis , viability assay , medicine , flow cytometry , chemistry , immunology , in vitro , biochemistry , psychiatry
Acitretin and matrine have been used in the treatment of psoriasis in China. This study was designed to investigate the role and related mechanisms of matrine alone and in combination with acitretin in the treatment of psoriasis in vitro and in vivo.