Open AccessIntestinal microbiota composition in patients with amyotrophic lateral sclerosis
Author(s) -
Chao-Di Zhai,
Jicui Zheng,
Bing-Chen An,
Hong-Fang Huang,
Zhou-Chun Tan
Publication year - 2019
Publication title -
chinese medical journal/chinese medical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 63
eISSN - 2542-5641
pISSN - 0366-6999
DOI - 10.1097/cm9.0000000000000351
Subject(s) - gut flora , firmicutes , feces , bacteroidetes , biology , amyotrophic lateral sclerosis , bacteroides , microbiology and biotechnology , metabolite , relative species abundance , composition (language) , food science , physiology , zoology , medicine , abundance (ecology) , bacteria , ecology , biochemistry , 16s ribosomal rna , genetics , disease , linguistics , philosophy
Emerging evidences have indicated that the composition of gut microbiota was significantly influenced by central nervous system diseases. The digestion and metabolism disturbances of patients with amyotrophic lateral sclerosis (ALS) might be strongly associated with ALS; however, this has rarely been evaluated in these populations. This study was to evaluate bacterial and archaeal composition of gut flora and the corresponding metabolism performance of these micro-organisms in fecal samples of patients with ALS.