Open AccessOptical coherence tomography findings in chronic progressive external ophthalmoplegia
Author(s) -
Yuan Wu,
Lei Kang,
Hailong Wu,
Yue Hou,
Zhaoxia Wang
Publication year - 2019
Publication title -
chinese medical journal/chinese medical journal
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 63
eISSN - 2542-5641
pISSN - 0366-6999
DOI - 10.1097/cm9.0000000000000262
Subject(s) - nerve fiber layer , retinal , medicine , ophthalmology , fundus (uterus) , optic nerve , optical coherence tomography , chronic progressive external ophthalmoplegia , mitochondrial dna , mitochondrial myopathy , biology , biochemistry , gene
Chronic progressive external ophthalmoplegia (CPEO) is a mitochondrial encephalomyopathy caused by multiple mtDNA abnormalities. There is little information about the changes of ocular fundus with CPEO. The aim of this work was to measure and evaluate changes in the macular retinal thickness and optic nerve head in patients with CPEO using spectral-domain optical coherence tomography and to compare the findings with those of healthy individuals.