Open AccessPlasma levels of receptor interacting protein kinase-3 correlated with coronary artery disease
Author(s) -
Xiaomin Hu,
Xi Chen,
Haiyu Pang,
Honghong Liu,
Peipei Chen,
JingShan Shi,
Si Tang,
Zhihong Wu,
Shuyang Zhang
Publication year - 2019
Publication title -
chinese medical journal/chinese medical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 63
eISSN - 2542-5641
pISSN - 0366-6999
DOI - 10.1097/cm9.0000000000000225
Subject(s) - coronary artery disease , medicine , cardiology , acute coronary syndrome , myocardial infarction , confidence interval , quartile , unstable angina , odds ratio , necroptosis , logistic regression , apoptosis , biology , biochemistry , programmed cell death
Necroptosis plays an important role in human atherosclerosis and atheroma development. Since receptor interacting protein kinase-3 (RIP3) acts as a key mediator of necroptosis, this study aimed to explore its relationship between plasma RIP3 levels and coronary artery disease (CAD) and discover a potential new biomarker for screening CAD subtypes and severity.