Open AccessCharacteristic dysbiosis of gut microbiota of Chinese patients with diarrhea-predominant irritable bowel syndrome by an insight into the pan-microbiome
Author(s) -
Zhe Wang,
Congmin Xu,
Yixuan Liu,
Xiaoqi Wang,
Zhigang Lu,
Mo Li,
Shiwen Zhu,
Zheng Xie,
Peihong Wang,
Liping Duan,
Huaiqiu Zhu
Publication year - 2019
Publication title -
chinese medical journal/chinese medical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 63
eISSN - 2542-5641
pISSN - 0366-6999
DOI - 10.1097/cm9.0000000000000192
Subject(s) - irritable bowel syndrome , dysbiosis , bacteroidetes , diarrhea , gastroenterology , microbiome , medicine , gut flora , population , firmicutes , feces , biology , immunology , 16s ribosomal rna , bioinformatics , microbiology and biotechnology , genetics , environmental health , bacteria
Irritable bowel syndrome (IBS) is reported associated with the alteration of gut microbial composition termed as dysbiosis. However, the pathogenic mechanism of IBS remains unclear, while the studies of Chinese individuals are scarce. This study aimed to understand the concept of dysbiosis among patients with Chinese diarrhea-predominant IBS (IBS-D), as a degree of variance between the gut microbiomes of IBS-D population and that of a healthy population.