Open AccessEffects of propofol, dexmedetomidine, and midazolam on postoperative cognitive dysfunction in elderly patients
Author(s) -
Weixia Li,
Ruyi Luo,
Chao Chen,
Xiang Li,
Jing-Sheng Ao,
Yue Liu,
Yongqiang Yin
Publication year - 2019
Publication title -
chinese medical journal/chinese medical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 63
eISSN - 2542-5641
pISSN - 0366-6999
DOI - 10.1097/cm9.0000000000000098
Subject(s) - dexmedetomidine , medicine , propofol , anesthesia , midazolam , sedation , postoperative cognitive dysfunction , sedative , randomized controlled trial , bispectral index , incidence (geometry) , surgery , cognition , physics , psychiatry , optics
Postoperative cognitive dysfunction (POCD) is a serious complication after surgery, especially in elderly patients. The anesthesia technique is a potentially modifiable risk factor for POCD. This study assessed the effects of dexmedetomidine, propofol or midazolam sedation on POCD in elderly patients who underwent hip or knee replacement under spinal anesthesia.