Open AccessSingle-cell sequencing in hematology
Author(s) -
Charlotte Brierley,
Adam J. Mead
Publication year - 2020
Publication title -
current opinion in oncology/current opinion in oncology, with cancerlit
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.297
H-Index - 95
eISSN - 1080-8140
pISSN - 1040-8746
DOI - 10.1097/cco.0000000000000613
Subject(s) - medicine , hematology , computational biology , haematopoiesis , stem cell , myeloid , bioinformatics , progenitor cell , cancer research , biology , genetics
In this review, we highlight key recent insights into hematopoiesis and hematological malignancies through the application of novel single-cell approaches. We particularly focus on biological insights made through the study of stem/progenitors cells in myeloid malignancy at single-cell resolution.