An update on clinical trials of targeted therapies in thyroid cancer
Author(s) -
Sigurdís Haraldsdóttir,
Manisha H. Shah
Publication year - 2013
Publication title -
current opinion in oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.297
H-Index - 95
eISSN - 1080-8140
pISSN - 1040-8746
DOI - 10.1097/cco.0000000000000029
Subject(s) - medicine , vandetanib , cabozantinib , sorafenib , thyroid cancer , medullary thyroid cancer , targeted therapy , clinical trial , oncology , adverse effect , cancer , hepatocellular carcinoma
Several new targeted therapies with multikinase inhibitors targeting vascular endothelial growth factor (VEGF), rearranged during transfection and v-raf murine sarcoma viral oncogene homolog B1 pathways have been tested in clinical trials for radioiodine-refractory differentiated thyroid cancer (DTC) and medullary thyroid cancer (MTC) in the past 10 years.
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