Open AccessUse of Airway Pressure Release Ventilation in Patients With Acute Respiratory Failure Due to COVID-19: Results of a Single-Center Randomized Controlled Trial*
Author(s) -
Miguel IbarraEstrada,
Yessica García-Salas,
Eduardo Mireles-Cabodevila,
José A López-Pulgarín,
Quetzalcóatl Chávez-Peña,
Roxana García-Salcido,
Julio C Mijangos-Méndez,
Guadalupe Aguirre-Ávalos
Publication year - 2021
Publication title -
critical care medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.002
H-Index - 271
eISSN - 1530-0293
pISSN - 0090-3493
DOI - 10.1097/ccm.0000000000005312
Subject(s) - medicine , tidal volume , ventilation (architecture) , anesthesia , mechanical ventilation , mean airway pressure , airway , continuous positive airway pressure , randomized controlled trial , pressure support ventilation , intubation , intensive care , respiratory distress , respiratory system , intensive care medicine , mechanical engineering , obstructive sleep apnea , engineering
Airway pressure release ventilation is a ventilatory mode characterized by a mandatory inverse inspiratory:expiratory ratio with a very short expiratory phase, aimed to avoid derecruitment and allow spontaneous breathing. Recent basic and clinical evidence suggests that this mode could be associated with improved outcomes in patients with acute respiratory distress syndrome. The aim of this study was to compare the outcomes between airway pressure release ventilation and traditional ventilation targeting low tidal volume, in patients with severe coronavirus disease 2019.