Open AccessThe Effectiveness of High-Flow Nasal Cannula in Coronavirus Disease 2019 Pneumonia: A Retrospective Cohort Study
Author(s) -
Michael S Burnim,
Kunbo Wang,
William Checkley,
Eric P. Nolley,
Yanxun Xu,
Brian T. Garibaldi
Publication year - 2022
Publication title -
critical care medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.002
H-Index - 271
eISSN - 1530-0293
pISSN - 0090-3493
DOI - 10.1097/ccm.0000000000005309
Subject(s) - medicine , nasal cannula , interquartile range , cannula , hazard ratio , mechanical ventilation , proportional hazards model , anesthesia , pneumonia , surgery , confidence interval
High-flow nasal cannula is widely used in acute hypoxemic respiratory failure due to coronavirus disease 2019, yet data regarding its effectiveness is lacking. More evidence is needed to guide patient selection, timing of high-flow nasal cannula initiation, and resource allocation. We aimed to assess time to discharge and time to death in severe coronavirus disease 2019 in patients treated with high-flow nasal cannula compared with matched controls. We also evaluated the ability of the respiratory rate-oxygenation ratio to predict progression to invasive mechanical ventilation.