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Comparison of Circulating Immune Cells Profiles and Kinetics Between Coronavirus Disease 2019 and Bacterial Sepsis*
Author(s) -
Charles de Roquetaillade,
Sehmi Mansouri,
Caren Brumpt,
Marie Neuwirth,
Sébastian Voicu,
Matthieu Le Dorze,
Candice Fontaine,
Romain Barthélémy,
Étienne Gayat,
Bruno Mégarbane,
Alexandre Mebazaa,
Benjamin Chousterman
Publication year - 2021
Publication title -
critical care medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.002
H-Index - 271
eISSN - 1530-0293
pISSN - 0090-3493
DOI - 10.1097/ccm.0000000000005088
Subject(s) - neutrophilia , medicine , immunology , coronavirus , immune system , cd14 , immunophenotyping , sepsis , eosinophilia , disease , antigen , infectious disease (medical specialty) , covid-19
Although clinical presentation of coronavirus disease 2019 has been extensively described, immune response to severe acute respiratory syndrome coronavirus 2 remains yet not fully understood. Similarities with bacterial sepsis were observed; however, few studies specifically addressed differences of immune response between both conditions. Here, we report a longitudinal analysis of the immune response in coronavirus disease 2019 patients, its correlation with outcome, and comparison between severe coronavirus disease 2019 patients and septic patients.

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