Open AccessPlasma Nucleosomes Are Associated With Mortality in Pediatric Acute Respiratory Distress Syndrome
Author(s) -
Nadir Yehya,
Hossein Fazelinia,
Gladys Gray Lawrence,
Lynn A. Spruce,
Mark Mai,
G. Scott Worthen,
Jason D. Christie
Publication year - 2021
Publication title -
critical care medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.002
H-Index - 271
eISSN - 1530-0293
pISSN - 0090-3493
DOI - 10.1097/ccm.0000000000004923
Subject(s) - medicine , interquartile range , respiratory distress , sepsis , odds ratio , anesthesia
Circulating nucleosomes and their component histones have been implicated as pathogenic in sepsis and acute respiratory distress syndrome in adults. However, their role in pediatric acute respiratory distress syndrome is unknown.