Open AccessA Comparison of Sepsis-2 (Systemic Inflammatory Response Syndrome Based) to Sepsis-3 (Sequential Organ Failure Assessment Based) Definitions—A Multicenter Retrospective Study*
Author(s) -
Milo Engoren,
Troy G. Seelhammer,
Robert E. Freundlich,
Michael D. Maile,
Matthew Sigakis,
Thomas A. Schwann
Publication year - 2020
Publication title -
critical care medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.002
H-Index - 271
eISSN - 1530-0293
pISSN - 0090-3493
DOI - 10.1097/ccm.0000000000004449
Subject(s) - sepsis , medicine , systemic inflammatory response syndrome , concordance , organ dysfunction , retrospective cohort study , intensive care medicine
Recently, the definition of sepsis has changed from a physiologic derangement (Sepsis-1 and -2) to organ dysfunction (Sepsis-3) based. We sought to determine the concordance between the different sepsis phenotypes and how that affected mortality.