Open AccessLFZ-4-46, a tetrahydroisoquinoline derivative, induces apoptosis and cell cycle arrest via induction of DNA damage and activation of MAPKs pathway in cancer cells
Author(s) -
Lili Xu,
Guozheng Huang,
Zhihui Zhu,
Shasha Tian,
Yingying Wei,
Huanwu Hong,
Xiaowei Lu,
Ying Li,
Feize Liu,
Huajun Zhao
Publication year - 2021
Publication title -
anti-cancer drugs
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.651
H-Index - 93
eISSN - 1473-5741
pISSN - 0959-4973
DOI - 10.1097/cad.0000000000001077
Subject(s) - apoptosis , dna damage , comet assay , viability assay , cell cycle checkpoint , cell cycle , cancer cell , flow cytometry , biology , microbiology and biotechnology , cancer research , chemistry , dna , cancer , biochemistry , genetics