Open AccessSynthetic Bone Graft Substitute for Treatment of Unicameral Bone Cysts
Author(s) -
Carl Nunziato,
John Williams,
Ronald P. Williams
Publication year - 2020
Publication title -
journal of pediatric orthopaedics/journal of pediatric orthopedics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.318
H-Index - 96
eISSN - 1539-2570
pISSN - 0271-6798
DOI - 10.1097/bpo.0000000000001680
Subject(s) - medicine , surgery , demineralized bone matrix , medullary cavity , bone healing , amplifier , dbm , cmos , electronic engineering , engineering
Treatments for unicameral bone cysts (UBCs) have high documented failure rates (27% to 63%) because of recurrence or persistence of the cyst, similar to nonoperative management. Recent evidence suggests that filling of the defect with a synthetic bone graft substitute (SBGS) supports the weakened cortex and promotes new bone growth. A calcium sulfate, brushite, calcium phosphate, composite graft material (PRODENSE, Wright Medical, Memphis, TN) has been evaluated as a substitute for autogenous or allogenous graft in animal and human studies. The purpose of this study was to compare the rates of revision surgery in patients treated for UBCs with an SBGS compared with historical treatments with allograft or autologous bone marrow aspirate.