Open AccessAnti-Infection Trauma Devices With Drug Release and Nonfouling Surface Modification
Author(s) -
Hao Wang,
Karen A. Schultz,
Koby Elias,
M. Stachowski,
Christopher Loose
Publication year - 2014
Publication title -
journal of orthopaedic trauma
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.221
H-Index - 121
eISSN - 1531-2291
pISSN - 0890-5339
DOI - 10.1097/bot.0000000000000065
Subject(s) - biocompatibility , surface modification , biofilm , titanium , chlorhexidine , ex vivo , biomedical engineering , scanning electron microscope , materials science , medicine , nuclear chemistry , chemical engineering , composite material , dentistry , chemistry , in vitro , biochemistry , bacteria , biology , engineering , metallurgy , genetics
By coupling an antimicrobial release with a highly nonfouling betaine modification on titanium, this approach innovatively addresses the initial bacterial challenge and the longer term biofilm formation on trauma devices.