Open AccessThe metabolic signature of T cells in rheumatoid arthritis
Author(s) -
Cornelia M. Weyand,
Bowen Wu,
Jörg J. Goronzy
Publication year - 2020
Publication title -
current opinion in rheumatology/current opinion in rheumatology, with evaluated medline
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.452
H-Index - 112
eISSN - 1080-8175
pISSN - 1040-8711
DOI - 10.1097/bor.0000000000000683
Subject(s) - medicine , rheumatoid arthritis , signature (topology) , mathematics , geometry
Rheumatoid arthritis (RA) is a prototypic autoimmune disease manifesting as chronic inflammation of the synovium and leading to acceleration of cardiovascular disease and shortening of life expectancy. The basic defect causing autoimmunity has remained elusive, but recent insights have challenged the notion that autoantigen is the core driver.