Open AccessLupus nephritis: challenges and progress
Author(s) -
Anne Davidson,
Cynthia Aranow,
Meggan Mackay
Publication year - 2019
Publication title -
current opinion in rheumatology/current opinion in rheumatology, with evaluated medline
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.452
H-Index - 112
eISSN - 1080-8175
pISSN - 1040-8711
DOI - 10.1097/bor.0000000000000642
Subject(s) - medicine , lupus nephritis , intensive care medicine , disease , clinical trial , systemic lupus erythematosus , translational research , immunology , pathology
The management of lupus nephritis remains unsatisfactory due to insufficiently effective treatment regimens and the dearth of reliable predictors of disease onset or progression to guide individualized therapeutic decisions. This review summarizes new findings related to lupus nephritis over the last 18 months and discusses clinical needs that should be considered to advance trials of mechanism-based therapeutic strategies.