Open AccessCommittee Opinion No. 527
Publication year - 2012
Publication title -
obstetrics and gynecology (new york. 1953. online)/obstetrics and gynecology
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 2.664
H-Index - 220
eISSN - 1873-233X
pISSN - 0029-7844
DOI - 10.1097/aog.0b013e31825af3c6
Subject(s) - medicine , disease , identification (biology) , genetic testing , clinical trial , cancer , bioinformatics , intensive care medicine , personalized medicine , pathology , biology , botany
Advances in genetic technologies have led to the identification of hundreds of single that are associated with a variety of complex diseases, including cancer, diabetes, cardiovascular disease, and Alzheimer disease. Although personalized genomic tests that provide information regarding the risk of development of multiple diseases may be important tools in the near future, their use is not recommended outside of a clinical trial until these tests are validated as clinically useful in appropriately designed prospective studies.Testing for single-gene disorders should be approached in accordance with accepted guidelines that address the evaluation and management of these specific diseases.