Open AccessRhythmic Change of Cortical Hemodynamic Signals Associated with Ongoing Nociception in Awake and Anesthetized Individuals: An Exploratory Functional Near Infrared Spectroscopy Study
Author(s) -
Ke Peng,
Keerthana Deepti Karunakaran,
Arielle Lee,
Andrea D Gomez-Morad,
Robert F. Labadie,
Arielle MizrahiArnaud,
Delany Berry,
Barry D. Kussman,
David Zurakowski,
Lyle J. Micheli,
Lino Becerra,
David Borsook
Publication year - 2021
Publication title -
anesthesiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.874
H-Index - 234
eISSN - 1528-1175
pISSN - 0003-3022
DOI - 10.1097/aln.0000000000003986
Subject(s) - medicine , anesthesia , nociception , hemodynamics , noxious stimulus , stimulation , haemodynamic response , heart rate , blood pressure , receptor
Patients undergoing surgical procedures are vulnerable to repetitive evoked or ongoing nociceptive barrage. Using functional near infrared spectroscopy, the authors aimed to evaluate the cortical hemodynamic signal power changes during ongoing nociception in healthy awake volunteers and in surgical patients under general anesthesia. The authors hypothesized that ongoing nociception to heat or surgical trauma would induce reductions in the power of cortical low-frequency hemodynamic oscillations in a similar manner as previously reported using functional magnetic resonance imaging for ongoing pain.