Open AccessA Subgroup of Chronic Low Back Pain Patients With Central Sensitization
Author(s) -
Kosaku Aoyagi,
Jia He,
Andrea L. Nicol,
Daniel J. Clauw,
Patricia Kluding,
Stephen Jernigan,
Neena Sharma
Publication year - 2019
Publication title -
the clinical journal of pain/the clinical journal of pain
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.109
H-Index - 126
eISSN - 1536-5409
pISSN - 0749-8047
DOI - 10.1097/ajp.0000000000000755
Subject(s) - medicine , fibromyalgia , psychosocial , chronic pain , depression (economics) , anxiety , physical therapy , psychiatry , economics , macroeconomics
Our knowledge of central sensitization (CS) in chronic low back pain (CLBP) is limited. 2011 fibromyalgia criteria and severity scales (2011 FM survey) have been used to determine FM positive as a surrogate of CS. The major features of CS including widespread hyperalgesia and dysfunction of the descending inhibitory pathways can be identified by pressure pain threshold (PPT) and conditioned pain modulation (CPM) tests. The purpose of the study was to examine neurophysiological characteristics and psychosocial symptoms in a subgroup of FM-positive CLBP compared with FM-negative CLBP patients.