Open AccessSustained-release Oral Hydromorphone for the Treatment of Opioid Use Disorder
Author(s) -
Vivian Braithwaite,
Christopher Fairgrieve,
Seonaid Nolan
Publication year - 2019
Publication title -
journal of addiction medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.264
H-Index - 42
eISSN - 1935-3227
pISSN - 1932-0620
DOI - 10.1097/adm.0000000000000585
Subject(s) - hydromorphone , medicine , opioid use disorder , methadone , opioid , oxycodone , anesthesia , buprenorphine , opioid overdose , methadone maintenance , polysubstance dependence , intensive care medicine , substance abuse , (+) naloxone , psychiatry , receptor
In 2017, almost 50,000 Americans and over 4000 Canadians died from an opioid overdose. Accordingly, an urgent need exists to improve access to evidence-based treatment for opioid addiction, and also to develop and evaluate alternative treatment options for opioid use disorder (OUD). We present a case of a patient with OUD who was successfully switched and managed on oral hydromorphone after development of a prolonged QTc interval on methadone.