Open AccessNovel vaccines for allergen-specific immunotherapy
Author(s) -
Oluwatoyin Akinfenwa,
Azahara Rodríguez-Domínguez,
Susanne Vrtala,
Rudolf Valenta,
Raffaela Campana
Publication year - 2020
Publication title -
current opinion in allergy and clinical immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.94
H-Index - 84
eISSN - 1528-4050
pISSN - 1473-6322
DOI - 10.1097/aci.0000000000000706
Subject(s) - medicine , allergen , allergen immunotherapy , allergy , immunology , immunoglobulin e , immunization , immunotherapy , vaccination , desensitization (medicine) , antibody , immune system , receptor
Allergen-specific immunotherapy (AIT) is a highly economic, effective and disease-modifying form of allergy treatment but requires accurate prescription and monitoring. New molecular approaches are currently under development to improve AIT by reducing treatment-related side effects, cumbersome protocols and patients' compliance. We review the current advances regarding refined diagnosis for prescription and monitoring of AIT and the development of novel molecular vaccines for AIT. Finally, we discuss prophylactic application of AIT.