Open AccessVery early-onset inflammatory bowel disease: an integrated approach
Author(s) -
Kathleen E. Sullivan,
Máire A. Conrad,
Judith R. Kelsen
Publication year - 2018
Publication title -
current opinion in allergy and clinical immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.94
H-Index - 84
eISSN - 1528-4050
pISSN - 1473-6322
DOI - 10.1097/aci.0000000000000484
Subject(s) - medicine , inflammatory bowel disease , disease , intensive care medicine , exome sequencing , immune dysregulation , mutation , biochemistry , chemistry , gene
Immune dysregulation disorders are among the most rapidly growing set of inborn errors of immunity. One particular subset is the category where early-onset inflammatory bowel disease (IBD) is the most common manifestation. These disorders are being increasingly appreciated although there has been minimal effort to articulate a unified approach to their diagnosis and management. This review will cover current thinking and strategies related to diagnosis and management of very early-onset IBD.